Norbrook Closamectin Injection For Cattle & Sheep

Closamectin Injection for Cattle and Sheep contains ivermectin and closantel and provides advanced fluke, worm and external parasite control in one convenient injection for both cattle and sheep. Cattle- treats liver fluke, gastrointestinal worms, lungworms, eyeworms, cattle grubs, mites and lice. Sheep- treats liver fluke, gastrointestinal worms, trematodes, lungworm, nasal bots and mites.

Active Ingredient
Each ml contains: 5 mg Ivermectin, 125 mg Closantel (as Closantel sodium dihydrate)

Solution for injection. A clear amber solution free from visible particles

Indications
Cattle: For the treatment of mixed trematode (fluke) and nematode or arthropod infestations due to gastrointestinal roundworms, lungworms, eyeworms, warbles, mites and lice of cattle. Gastrointestinal roundworms Ostertagia ostertagi (including inhibited larval stages), Ostertagia lyrata (adult), Haemonchus placei (adult and immature), Trichostrongylus axei (adult and immature), Trichostrongylus colubriformis (adult and immature), Cooperia oncophora (adult and immature), Cooperia punctata (adult and immature), Cooperia pectinata (adult and immature), Oesophagostomum radiatum (adult and immature), Nematodirus helvetianus(adult), Nematodirus spathiger(adult), Strongyloides papillosus(adult), Bunostomum phlebotomum (adult and immature), Toxocara vitulorum (adult), Trichuris spp. Lungworms: Dictyocaulus viviparus (adult and 4th stage larvae) Liver Fluke (trematodes): Fasciola gigantica, Fasciola hepatica Treatment of fluke at 12 weeks (mature) >99% efficacy. Treatment of fluke from 7 weeks (late immature) >90% efficacy Eyeworms (adult) Thelazia spp Cattle grubs (parasitic stages) Hypoderma bovis, Hypoderma lineatum Lice Linognathus vituli, Haematopinus eurysternus, Solenopotes capillatus Mange Mites Psoroptes ovis (syn P communis var bovis), Sarcoptes scabiei var bovis. Closamectin Injection may also be used as an aid in the control of the biting louse Damalinia bovis and the mange mite Chorioptes bovis, but complete elimination may not occur. Persistent activity in cattle When cattle have to graze on pasture contaminated with infective larvae of cattle nematodes, treatment with Closamectin Injection at the recommended dose rate of 200 mg ivermectin per kg bodyweight and 5 mg closantel per kg bodyweight controls re-infection with: Prolonged activity Dictyocaulus viviparus: Up to 21 days, Ostertagia ostertagi: Up to 21 days, Oesophagostomum radiatum: Up to 21 days, Cooperia spp: Up to 14 days, Trichostrongylus axei: Up to 14 days, Haemonchus placei: Up to 14 days.

Sheep: For the treatment of mixed trematode (fluke) and nematode or arthropod infestations due to gastrointestinal roundworms, trematodes, lungworms, nasal bots and mites of sheep. Gastrointestinal roundworms Ostertagia circumcincta (including inhibited L4), Ostertagia trifurcata (adult and L4), Haemonchus contortus (including inhibited L4), Trichostrongylus axei (adult), Trichostrongylus colubriformis (adult and L4), T. vitrinus (adult) Cooperia curticei (adult and L4), Oesophagostomum columbianum (adult and L4), O. venulosum (adult) Chabertia ovina (adult and L4) Nematodirus filicollis (adult and L4), Trichuris ovis (adult). [L4 = fourth stage larvae] Lungworms Dictyocaulus filaria (adult and 4th stage larvae) Protostrongylus rufescens (adult) Liver Fluke (trematodes) Fasciola gigantica, Fasciola hepatica Treatment of fluke at 12 weeks (mature) >95% efficacy. Treatment of fluke at 7 weeks (late immature) 100% efficacy. Nasal Bots Oestrus ovis Mange Mites Psoroptes ovis (Treatment requires a second injection of an ivermectin-only containing product 7 days later). Benzimidazole resistant strains of Haemonchus contortus and Ostertagia circumcincta are also controlled.

Dosage
Closamectin Injection should be administered at a dosage rate of 200 mg ivermectin per kg bodyweight and 5 mg closantel per kg bodyweight (1 ml per 25 kg). It should only be injected subcutaneously into the neck. A maximum dose of 10ml should be administered at any one site with any residual volume administered at another site in the neck. A sterile 16-gauge, one-inch needle is recommended. For the treatment and control of sheep scab an injection of Closamectin Injection for Sheep may be administered but must be followed with a second injection of an ivermectin only product seven days after the initial injection to treat clinical signs of scab and to eliminate mites. This injection should be administered at the other side of the neck. This product does not contain an antimicrobial preservative. Swab septum before removing each dose. Use a dry sterile needle and syringe. For 250 ml and 500 ml pack sizes, use of a multiple dose syringe is recommended. To refill the syringe, use of a draw-off needle is recommended to avoid excessive broaching of the stopper. Do not exceed 40 broachings per vial. If more than 40 broachings are required, use of a draw off needle is recommended. The timing for treatment should be based on epidemiological factors and should be customised for each individual farm. As with other anthelmintics, veterinary advice should be sought on appropriate dosing programmes and stock management to achieve adequate parasite control and reduce the likelihood of resistance developing. To ensure administration of a correct dose, bodyweight should be determined as accurately as possible- accuracy of the dosing device should be checked. If animals are to be treated collectively rather than individually they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or over-dosing.

Legal Category: POM-VPS.

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